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Enzymes of the cytochrome p system may present polymorphisms that can explain the individual interacciones farmacologicas in the response to drugs or the appearance of druginteractions. However, a major characteristic to be evaluated when choosing an antifungal agent apart from antifungal spectrum, pharmacokinetics and adverse effects is the absence of significant drug interactions. Pdi and their characteristics in the therapeutic plan of. Amphotericin b lacks interactions but may cause renal dysfunction, leading to the accumulation of renally metabolized drugs. Absorcion pg,cambio en ph gastrico, coadministracion con alimentos, etc.
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